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KMID : 0032220150270010082
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Annals of Dermatology
2015 Volume.27 No. 1 p.82 ~ p.86
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Treatment of Patients with Refractory Atopic Dermatitis Sensitized to House Dust Mites by Using Sublingual Allergen Immunotherapy
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Choi Joon-Seok
Ryu Ha-Ryeong
Yoon Cheol-Hyun
Kim Ji-Hoon
Baek Jin-Ok
Roh Joo-Young
Lee Jong-Rok
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Abstract
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Even though atopic dermatitis (AD) is one of the most com-mon chronic inflammatory skin diseases, its treatment re-mains a challenge in clinical practice, with most approaches limited to symptomatic, unspecific anti-inflammatory, or im-munosuppressive treatments. Many studies have shown AD to have multiple causes that activate complex immuno-logical and inflammatory pathways. However, aeroaller-gens, and especially the house dust mite (HDM), play a rele-vant role in the elicitation or exacerbation of eczematous le-sions in many AD patients. Accordingly, allergen-specific immunotherapy has been used in AD patients with the aim of redirecting inappropriate immune responses. Here, we re-port three cases of refractory AD sensitized to HDM who were treated with sublingual immunotherapy. (Ann Dermatol 27(1) 82∼86, 2015)
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KEYWORD
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Atopic dermatitis, Pyroglyphidae, Sublingual immunothe-rapy
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